Through the centuries, neem leaf has been the first choice of healthcare practitioners and researchers, in large part because it's easy to harvest and available year-round. Neem leaf is particularly suited for acute conditions, but also has higher levels of important flavonoids like quercitrin and rutin. Neem bark is not used as often either traditionally or in modern practice, but it does offer three significant advantages. - First, one of the few clinical studies conducted with neem looks how neem bark helps moderate levels of stomach acid. That's obviously as issue for people with gastrointestinal issues, but also may be an important consideration for people who take pain medications like aspirin or ibuprofen.
- Secondly, it contains higher levels of nimbidin, which reduces production of nitric oxides and prostaglandins, making it a better choice for people and pets with minor inflammation.
- Finally, it contains higher levels of some key antioxidants including catechin and gallo-catechin as well as having a higher ORAC (Oxygen Radical Absorbance Capacity) value than neem leaf.
If you're still not sure which is best, you can use both neem leaf and neem bark extracts – just divide the recommended dose in half because they do have many compounds in common. | 
